RECURRENT APHTHOUS STOMATITIS (RAS)

RECURRENT APHTHOUS STOMATITIS (RAS)

Afif Nurul Hidayati, Sunarso Suyoso

Bag./SMF Ilmu Kesehatan Kulit dan Kelamin

FK UNAIR/RSU Dr. Soetomo

ABSTRAK:

Recurrent aphthous stomatitis (RAS) merupakan kelainan pada rongga mulut berupa ulkus yang penyebabnya belum diketahui dengan pasti, merupakan kondisi kronik dan sering terjadi berulang, biasanya onsetnya terjadi pada masa kanak-kanak atau masa pertumbuhan dan frekuensi serta keparahannya cenderung menurun seiring dengan meningkatnya usia. Diagnosis banding “aphthae” meliputi penyakit vesikobulous, granuloma, dan karsinoma sel skuamosa. Terjadinya aphthous ulcers pada orang dewasa patut dicurigai kemungkinan adanya kelainan sistemik yang lebih komplek seperti Behcet’s syndrome atau inflammatory bowel disease. Penatalaksanaan meliputi koreksi penyakit yang menyertai atau faktor predisposisi yang menyebabkan, serta penggunaan bahan anti inflamasi topikal maupun sistemik atau obat-obat imunomodulator.

Kata kunci: aphthae, recurrent aphthous stomatitis, Behcet’s syndrome

ABSTRACT:

Recurrent aphthous stomatitis (RAS) is a chronic condition, usually with a childhood or adolescent onset and with a tendency to diminish in frequency and severity with age. Most patients are otherwise healthy. The differential diagnosis for “aphthae” includes vesicobullous diseases, granulomas, and even squamous cell carcinomas. The onset of aphthous-like lesions in adults suggests the possibility of developing a more complex systemic disorder such as Behcet’s syndrome or inflammatory bowel disease. Treatment includes correction of underlying disease or predisposing causes, and the use of topical and systemic anti-inflammatory agents or immunomodulating drugs.

Keywords: aphthae, recurrent aphthous stomatitis, Behcet’s syndrome.

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